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	<title>Comments on: Hitting three peeves with one stone</title>
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		<title>By: Andrew Yates</title>
		<link>http://biopinionated.com/2008/10/11/hitting-three-peeves-with-one-stone/#comment-191</link>
		<dc:creator><![CDATA[Andrew Yates]]></dc:creator>
		<pubDate>Sun, 12 Oct 2008 18:23:20 +0000</pubDate>
		<guid isPermaLink="false">http://sciphu.wordpress.com/?p=507#comment-191</guid>
		<description><![CDATA[Yes, it was only a metaphor for comparison.

Also, 23andMe has good reporting, and I&#039;m not aware of &lt;em&gt;better&lt;/em&gt; compilation reports like these. I do think that their penetrance estimate is too confident, particularly considering the incoherent estimates in all the literature, and that they should disclose exactly how they generated that number.]]></description>
		<content:encoded><![CDATA[<p>Yes, it was only a metaphor for comparison.</p>
<p>Also, 23andMe has good reporting, and I&#8217;m not aware of <em>better</em> compilation reports like these. I do think that their penetrance estimate is too confident, particularly considering the incoherent estimates in all the literature, and that they should disclose exactly how they generated that number.</p>
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		<title>By: sciphu</title>
		<link>http://biopinionated.com/2008/10/11/hitting-three-peeves-with-one-stone/#comment-190</link>
		<dc:creator><![CDATA[sciphu]]></dc:creator>
		<pubDate>Sun, 12 Oct 2008 11:20:35 +0000</pubDate>
		<guid isPermaLink="false">http://sciphu.wordpress.com/?p=507#comment-190</guid>
		<description><![CDATA[Andrew: Code is different in that you usually know it&#039;s function, and hence can discriminate between what is &quot;junk&quot; or not, - that&#039;s not always the case with DNA.

Michael: I like your definition of &quot;junk&quot;-DNA - &quot;DNA with NO function period.&quot;.  When is that statement true, that&#039;s my question. At what point do you know that a given piece of DNA has no function. My argument is that I have seen few examples where the &quot;junk&quot; conclusion was reached by that criterium. The label is very often put on &quot;DNA with no KNOWN function&quot;. Therefore, reporting that something is not &quot;junk&quot; anymore when a function has been ascribed to it, is not &quot;untrue&quot;. I also do not think one should shy away from admitting that science sometimes can be &quot;flighty and inconsistent&quot;, isn&#039;t that the nature of science sometimes and also the reason we keep refining our hypothesis and theories ?]]></description>
		<content:encoded><![CDATA[<p>Andrew: Code is different in that you usually know it&#8217;s function, and hence can discriminate between what is &#8220;junk&#8221; or not, &#8211; that&#8217;s not always the case with DNA.</p>
<p>Michael: I like your definition of &#8220;junk&#8221;-DNA &#8211; &#8220;DNA with NO function period.&#8221;.  When is that statement true, that&#8217;s my question. At what point do you know that a given piece of DNA has no function. My argument is that I have seen few examples where the &#8220;junk&#8221; conclusion was reached by that criterium. The label is very often put on &#8220;DNA with no KNOWN function&#8221;. Therefore, reporting that something is not &#8220;junk&#8221; anymore when a function has been ascribed to it, is not &#8220;untrue&#8221;. I also do not think one should shy away from admitting that science sometimes can be &#8220;flighty and inconsistent&#8221;, isn&#8217;t that the nature of science sometimes and also the reason we keep refining our hypothesis and theories ?</p>
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		<title>By: Michael Eisen</title>
		<link>http://biopinionated.com/2008/10/11/hitting-three-peeves-with-one-stone/#comment-189</link>
		<dc:creator><![CDATA[Michael Eisen]]></dc:creator>
		<pubDate>Sat, 11 Oct 2008 14:45:15 +0000</pubDate>
		<guid isPermaLink="false">http://sciphu.wordpress.com/?p=507#comment-189</guid>
		<description><![CDATA[The term &quot;junk DNA&quot; is not simply a catchall for pieces of DNA with no KNOWN function, it was specifically coined, and is nearly exclusively used, to refer to DNA with NO function period. These press releases aren&#039;t purporting to have discovered a function for a particular piece of DNA, they are claiming to have overturned the broad hypothesis that 95% of the human genome has no function - a hypothesis that we have long known to be false. 

And I certainly don&#039;t think scientists should be afraid of creationists in any way. Indeed, I think the best defense against creationism is loudly and unashamedly trumpeting everything we know about evolution. Whay I was pointing out is precisely the opposite - that there is a danger in continuing bring up ideas that we know to be untrue - even as straw men - because it makes evolutionary biology look flighty and inconsistent.]]></description>
		<content:encoded><![CDATA[<p>The term &#8220;junk DNA&#8221; is not simply a catchall for pieces of DNA with no KNOWN function, it was specifically coined, and is nearly exclusively used, to refer to DNA with NO function period. These press releases aren&#8217;t purporting to have discovered a function for a particular piece of DNA, they are claiming to have overturned the broad hypothesis that 95% of the human genome has no function &#8211; a hypothesis that we have long known to be false. </p>
<p>And I certainly don&#8217;t think scientists should be afraid of creationists in any way. Indeed, I think the best defense against creationism is loudly and unashamedly trumpeting everything we know about evolution. Whay I was pointing out is precisely the opposite &#8211; that there is a danger in continuing bring up ideas that we know to be untrue &#8211; even as straw men &#8211; because it makes evolutionary biology look flighty and inconsistent.</p>
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		<title>By: Andrew Yates</title>
		<link>http://biopinionated.com/2008/10/11/hitting-three-peeves-with-one-stone/#comment-188</link>
		<dc:creator><![CDATA[Andrew Yates]]></dc:creator>
		<pubDate>Sat, 11 Oct 2008 14:17:39 +0000</pubDate>
		<guid isPermaLink="false">http://sciphu.wordpress.com/?p=507#comment-188</guid>
		<description><![CDATA[I don&#039;t have any statistics handy, but computer code is mostly &quot;junk&quot; too: low density data, not instructions. Most computer code is a few lines of algorithm and everything else is either data, addresses, or &quot;this is that&quot; glue code.]]></description>
		<content:encoded><![CDATA[<p>I don&#8217;t have any statistics handy, but computer code is mostly &#8220;junk&#8221; too: low density data, not instructions. Most computer code is a few lines of algorithm and everything else is either data, addresses, or &#8220;this is that&#8221; glue code.</p>
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