On BioScience and Life and Such

Pharmacogenetics and Normal Variation

In Uncategorized on December 10, 2007 at 8:29 am

Argument: Doing pharmacogenetics is futile since the frequency of clinically relevant genomic variations does not differ between the patient population and the normal population.

Reply: Since the frequency of most of these genomic variations is high, you would need a large cohort to verify that no over-representation exists in your patient samples. In addition, a negative answer (no variation detected) is not the same as a useless answer, as it can be used to look for other reasons for the condition presented.


Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: