On BioScience and Life and Such

A tribute to Dr. Sergio Stagnaro, – consider yourself warned…

In Uncategorized on October 30, 2008 at 10:04 am

post to news.thinkgene.com

Such as problem is really difficult to resolve, when the interest of all individuals, i.e., drug companies and patients, is central. Every drug, if it’s such, must be burden by beside effects, sometimes dangerous. In addition, we must remember that the statement “post hoch ergo propter hoch” not always is right, according to Hume! In spite of the above mentioned remarks, in my opinion, if all physicians around the world would know precisely both Biophysical Semeiotic Constitutions and related inherited real risks, harmful results should be less numeorus.

If you are a regular blog/news reader, you are certain to come across writings from people with views removed, to a varying extent, from the mainstream. This applies not only to those who themselves blog or write news stories, but just as often, to the people that are commenting on these pieces.

Dr. Sergio Stagnaro is such a person. He seems not to have a blog on his own even though he is an obvious blogger-candidate. He is frequently commenting on other peoples web-writings voicing ideas and views (especially on diagnostics) that are well removed from the mainstream (rather on a mountain top somewhere, – not necessarily in the vicinity of any running liquid whatsoever). These are features that usually fits well in the blogging genre.

I’ve consequently, taken on the task of blogging some of his comments since he strikes me as an interesting person and I believe he means no harm. Admittedly, the risk of his ideas causing harm is hard for me to assess since I find myself unable to evaluate most of the medical points he is making (see the first and the last quotes in this post). But, I’ll take that risk – on to the quotes:

On climate change:

Surely, climate change is real, as states wisely Obama. On the contrary, I believe that NHS Programs are unfortunately stable all around the world, generating the present Mean Age of Medicine and – as a consequence – Psychological Terrorism. For instance read http://www.nature.com/news/2008/081006/full/news.2008.1154.html

On why there are so few women speaking at medical conferences” (in two parts):

Now I am an old and diseased man, as a consequence I am working exclusively with computers without attending and speaking at Italian Congresses, as usually in the past decades. I remember that I meet once numerous women, who spoke in so fascinating way, but your information gehnerally were OLD to me. In any case, they were really nice!


Dear Fi,
in my former comment there are two trivial errors.I wrote “your” information, instead of THEIR; “gehnerally” and not generally! In addition, I admitt that not ALL women were “really nice”.I should agree with cancelling both of messages.
Please, excuse me.

From NEJM on Diet and Risk of Type 2 Diabetes:

To the Editor: In their article on diet, lifestyle, and type 2 diabetes mellitus in women (Sept. 13 issue),1 Hu et al. point out that obesity is an important cause of type 2 diabetes mellitus. I wish to point out that since diabetes does not develop in all overweight women (or men, of course), there must be other factors that predispose patients to the condition, as I illustrated in earlier reports.2,3,4,5,6 Therefore diet is certainly important, but particularly for women and men for whom this overlooked risk factor is involved.

And I’ll include this to illustrate his frustration caused by the lack of response to his diagnostic methods (from bmj):


As I wrote recently (as usual without receiving any response, of course) in an open letter to Italian Health Minister Prof Sirchia …….

More on his diagnostic methods, from International Seminars in Surgical Oncology

Sergio Stagnaro (06 December 2007)  Biophysical Semeiotics Research Laboratory email


the authors write:”The typical clinical presentation of idiopathic granulomatous mastitis often mimics infection or malignancy”. Unfortunately, it’s clear that authors ignore Biophysical Semeiotics (1-5) (www.semeioticabiofisica.it). In addition, using breast cancer genetic risk assessment tools and going through the process of assessing breast cancer risk by this expensive way, can answer many women’s questions about what puts them at relatively higher or lower risk. Certainly such as evaluation is to expensive for both NHS and single patient, and not applicable on women (and men!, of course) on very large scale.

In fact, based on 51 year-long clinical experience, for all women (and men!), an original clinical assessement may be desirable that in a easy and reliable manner allows to recognize the possible presence of maternally-inherited CAEMH-dependent, Oncological Terrain and oncological Real Risk, conditio sine qua non of cancer (1, 2), without following with genetic testing, but ascertaining especially breast cancer oncological INHERITED “real risk” in well-defined breast quadrant(s), characterized by newborn-pathological, type I, subtype a) i.e., oncological, Endoarteriolar Blocking Devices (1-5). In addition, testing for mutations of breast cancer susceptibility genes or for their diminished expression adds to our ability to assess breast cancer risk at an individual level. Really, we cannot localise in a (or more) mamma quadrant the possible breast cancer risk in BRCA 1 and BRCA 2, as well as a lot of other gene mutations-positive women (and men!). Biophysical Semeiotics (http://www.semeioticabiofisica.it, Breast Cancer in Practical Application; Oncological Terrain) allows doctor to recognize firstly oncological terrain in a quantitative way, and then, bu “not” in all cases, of course, breast cancer real risk: individuals with oncological terrain do not show generally real risk in all biological systems (3). Interestingly, the absence of both Oncological Terrain and breast oncological “Real Risk”, the later in a subject with Oncological Terrain, excludes beyond every doubt the possibility of occurrence of breast cancer (2, 3). As a consequence, we can perform nowadays an efficacious clinical, primary prevention of breast cancer (4), on very large scale, based on the Single Patient Based Medicine (5-10), as suggests also Planning for the EU public Health Portal at URL:

http://www.google.it/search?q=cache:U5A-DtWmRDsJ:europa.eu.int/comm/health/ph_information/documents/ev_20030710_co01_en.pdf+single+patient+based+medicine+and+stagnaro&hl=it&ie=UTF-8 Pg 36.

Finally, “real” sentinel limphonodes are trigger-points for autoimmune syndrome (3)

And finally you have his own compilation of comments that you can find here.

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  1. Thanks to Nils Reinton, but also compliment!
    I admitt that ALL what he has referred in the blog…dedicated kindly to me … is correct, a part from overlooking the quality of my English, which is poor, medieval, distressing, autodidact.
    After that, I am preparing an article(English..) in two parts, wherein I justify my definition MEADLE AGES of today’s Medicine!
    If Nils Reinton send me an e-mail adress, I’ll send the paper for a possible publication, at least in “my” blog, even after editing it…in English.

    Greetings to all of you

  2. Dr. Stagnaro. You are more than welcome. I am glad that you liked my post. I would like to invite you to publish your article on http://www.sciphu.com, which is a publication alternative I think you may find suitable. To do this, you need a Google account (free). Send the e-mail address valid for the Google account to sciphu_at_sciphu_dot_com and I’ll give you write-access on sciphu.com. I suspect your paper has the potential to generate a lively discussion in the comment section, and welcome your submission.

  3. Dear Nils,
    I’dd be grateful to you, really clever and up-dated, if you kindly write me what accounts for the reason of the SILENCE of oncologists of all world, to whom I communicated the above-posted paper, asking their CRITICAL comment!
    In addition, the famous http://www.nature.com invites reader to visit your celebrated Blog: Top cited papers
    Nature blogs: http://blogs.nature.com/ Diet and Risk of Type 2 Diabetes, Paper Author: Sergio Stagnaro et al.
    Paper Posts: Linked to by 1 post.
    Nature blogs http://blogs.nature.com/posts?paper=669
    A tribute to Dr. Sergio Stagnaro, – consider yourself warned…
    Date: 05 Nov 2008.
    An italian proverb sounds “Silence means consent!”.
    Is it valid also for all Members of NCI, Isituto Europeo dei Tumori, Istituto Nazionale di Ricerca sul Cancro, Royal Swedish Academy of Science, London Royal Academy of Science, a.s.o.? In such case, therefore, I am right, saying that we are really living in Middle Ages of Medicine!

  4. Haha, he’s coming after me today. I love the Internet.

  5. I am glad, as well as disheartening at the same time, realizing that NOBODY all around the world, has critically commented (not to speak…confuted) my definition: Middle Ages of today’s Medicine. Glad, since the Silence is without doubt significant. Distressing, since such as behaviour is a paradygm of today’s Dark Ages!

  6. His claims are worth investigating.

    This Doctor has published hundreds of articles, over the years, in prestigious medical journals explaining his clinical approach.

    Is it possible that no one ever decided to perform a randomized double-blind trial?

    Thousands of scientists work investigating the effect of cancer on the sexual life of small animals worldwide.

    How come nobody is interested in investigating Dr Stagnaro’s method of predicting early, diabetes, cancer and cardiovascular disease?

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